Hemoglobin A1C Levels - Scientific Research

The results from scientific research studies are typically published by scientific journals so that others may read and benefit from the information. Collectively, this body of published research results is known as the "scientific literature." We have assembled a partial list of references to published scientific papers that are related to diabetes and A1c levels. Where possible a link is given to the scientific research publication itself.

A. J. Rose et. al. Does Opioid Therapy Affect Quality of Care for Diabetes Mellitus? Am J Manag Care 15(4):217-224 (2009)
Chantal Mathieu et. al. Efficacy and Safety of Dapagliflozin in Patients With Inadequately Controlled Type 1 Diabetes (the DEPICT-2 Study): 24-Week Results From a Randomized Controlled Trial Am Diabetes Care Sep 2018, 41 (9) 1938-1946 (2018)
C. J. Currie et. al. Survival as a Function of HbA1c in People With Type 2 Diabetes: A Retrospective Cohort Study. Lancet 375:481-489 (2010)
S. Arnold et. al. Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: a proof-of-concept study. Diabetes Care 33(7):1509-1515 (2010)
W. Duckworth et. al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med. 360:129-139 (2009)
A. S. Adams et. al. Medication adherence and racial differences in A1C control Diabetes Care Vol 31 No 5 916-21 (2008)
Y. J. Cheng et. al. Association of A1C and Fasting Plasma Glucose Levels With Diabetic Retinopathy Prevalence in the U.S. Population. Diabetes Care (2009);32:2027-2032
J.J. Holst et. al. GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in Diabetes. Diabetes Res Clin Pract Vol 85: 1-3 (2009)
M. E. Halkos et. al. Elevated preoperative hemoglobin A1c level is predictive of adverse events after coronary artery bypass surgery. Thorac Cardiovasc Surg (2008);136:631-640
Joo S, et. al. Habitual snoring is associated with elevated hemoglobin A1c levels in non-obese middle-aged adults. J Sleep Res Vol 15 No 4 437-44 (2006).
Herman GA, et. al. Pharmacokinetics and pharmacodynamic effects of the oral DPP-4 inhibitor sitagliptin in middle-aged obese subjects. J Clin Pharmacol Vol 46 876�886 (2006)
Fenton JJ, et. al. Quality of preventive care for diabetes: effects of visit frequency and competing demands. Ann Fam Med Vol 4 32-39 (2006)
Bonora E, et. al. Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus. Diabetologia Vol 49 846-854 (2006)
Lankisch M, et. al. Basal insulin and oral antihyperglycemic therapy (BOT) plus a single dose of insulin glusine at breakfast or at the predominant meal lower HbA1c in patients with type 2 diabetes. Diabetes 55 supplement 1, Abstract 514-P (2006)
D. M. Nathan, et al. Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy. Diabetes Care 29:1963�1972 (2006)
Heine RJ, et. al. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial. Ann Intern Med (2005) 143:559�569.
Roberto Gianani, George S. Eisenbarth. The stages of type 1A diabetes. Immunological Reviews 204:1, 232-249 (2005).
RHA Becker, et. al. Insulin glulisine, a new rapid-acting insulin analogue, displays a rapid time-action profile in obese non-diabetic subjects. Exp Clinical Endocrinol Diabetes (2005) 13: 435�443.
Rosenstock J, et. al. Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: a randomized, controlled trial. Ann Intern Med 2005; 143:549�558.
Edelman D, et al. Utility of hemoglobin A1c in predicting diabetes risk. J Gen Intern Med 19:1175-1180 (December 2004).
Sheehan MT. Current therapeutic options in type 2 diabetes mellitus: a practical approach. Clin Med Res (2003) 1:189�200.
Derr R, et al. Is HbA1c Affected by Glycemic Instability? Diabetes Care 26, 2728-2733 (2003).
Rohlfing CL, et. al. Defining the relationship between plasma glucose and HbA1c: analysis of glucose profiles and HbA1c in the Diabetes Control and Complications Trial. Diabetes Care Vol 25 275�278 (2002).
Chandalia M, et. al. Beneficial Effects of High Dietary Fiber Intake in Patients with Type 2 Diabetes Mellitus. N Engl J Med Vol 342 1392-1398 (2000).
Sidarov J, et. al. Disease Management for Diabetes Mellitus: Impact on Hemoglobin A1C. Am J Manag Care Vol 6 (11) 1217-1226 (2000).
Karjalainen J.A. et. al. A Bovine albumin peptide as a possible trigger of Insulin-dependent diabetes mellitus. N Engl J Med 327:302-307 (1992).
This study compared the levels of anti-BSA (bovine serum albumin) antibodies in the blood serum of children with insulin-dependent diabetes mellitus, healthy children, and adults.
A. G. Bertoni, Achieving control of diabetic risk factors in primary care settings. Am J Manag Care Apr 7(4):411-21 (2001)
Schwartz, J.S. et. al. Glycosylated hemoglobin assays in the management and diagnosis of diabetes mellitus. Ann Internal Med. Vol 101 710-713 (1984).
Rochman, H. Hemoglobin A1c and Diabetes Mellitus. Ann Clin Lab Sci. Vol 10 No 2 111-115 (1980).
Dolhofer, R. and Wieland, O. Increased glycosylation of serum albumin in diabetes mellitus. Diabetes vol 24 417-422 (1980).
Bunn, H. et. al. The glycosylation of hemoglobin: relevance to diabetes mellitus. Science Vol 200 No 4337 21-27 (April 1978).

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